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Imitrex

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Description

Common use

Sumatriptan is a drug that is used for treating migraine attacks with or without the presence of an aura, to relieve cluster headache attacks. Sumatriptan is a Specific and selective agonist of 5-HT1-serotonin receptors localized mainly in blood vessels of the brain. Migraine headaches are believed to be stipulated by widening of blood vessels in the brain. Sumatriptan causes vasoconstriction of the carotid arterial bed which provides extracranial and intracranial tissues with blood without a significant impact on cerebral blood flow. It also inhibits activity of receptor which are responsible for transmission of pain signals by nerves to the brain.

Dosage and direction

Treatment with Sumatripan should be done just before the starting of a migraine attack. Recommended oral dose of adults is 25-50 mg, the dose maybe increased up to 100 mg if necessary. The medication is effective at any stage of the attack but if it does not help during the attack additional dose should not be taken. Treatment with Sumatriptan should be continued to prevent the next attack. Tablet of Sumatriptan should be swallowed whole, take it with a big glass of water. Usual intranasal dose of 5-20 mg may be increased to the maximum dose of 40 mg daily.

Precautions

Sumatriptan is used only to treat an acute, classic migraine attack or a cluster headache, it should not be used for treatment of certain unusual types of migraine. Patients with uncontrolled high blood pressure should not use Sumatriptan.

Contraindications

Hypersensitivity, basal, ophtalmoplegic, hemiplegic forms of migraine, ischemic heart disease (including suspected it), angina (including angina Printsmetala), myocardial infarction (also in history), hypertension, peripheral arterial occlusive disease, stroke or transient cerebrovascular accident (also in history), liver and kidney failure. Cautiousness should be exercised in patients with epilepsy (including any condition with low epileptic threshold), hypertension, pregnancy, breastfeeding, in infants and adolescents (younger than 18 y.o.), in patients older than 65 y.o.; simultaneous intake of medications which contain ergotamine and its derivatives, MAO inhibitors, and also during the period of 14 days after their cancellation.

Possible side effect

This medication is usually well tolerated and adverse reactions are not expected. Most frequent side effects include pain or tightness in the chest or throat, tingling, flushing, weakness, dizziness, abdominal discomfort, sweating, nasal irritation, and injection site reactions. Allergic reactions as adverse reactions of organism to Sumatriptan are also possible.

Drug interaction

Co-administration with ergotamine and medications containing ergotamin may develop a continued spasm of blood vessels (the interval between administration of these medications must be at least 24 h). Interaction of Sumatriptan and MAO inhibitors (isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine (Matulane)) is also possible resulting in increased concentration of Sumatriptan. Concomitant use of Sumatriptan with selective serotonin reuptake inhibitors or SSRIs, including fluoxetine (Prozac), citalopram (Celexa), paroxetine (Paxil), and sertraline (Zoloft) or serotonin and norepinephrine reuptake inhibitors, including venlafaxine (Effexor), duloxetine (Cymbalta), and desvenlafaxine (Pristiq) may promote weakness, hyperreflexia and poor coordination of movements.

Missed dose

Sumatriptan is not meant for regular use, it is taken only during an attack.

Overdose

Be especially attentive to such symptoms as bluish tinge to the skin, convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor as they may be signs of Sumatriptan overdose. Inform your health care advisor immediately about your condition nor seek for emergency medical help.

Storage

Store this medication at a temperature of 2-30 C (36-86 F) in a tight container resistant to light and moisture.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Additional information

Dose

100mg, 25mg, 50mg

Pack

10pills, 120pills, 20pills, 30pills, 60pills, 90pills

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Description
ContentCommon use

Sumatriptan is a drug that is used for treating migraine attacks with or without the presence of an aura, to relieve cluster headache attacks. Sumatriptan is a Specific and selective agonist of 5-HT1-serotonin receptors localized mainly in blood vessels of the brain. Migraine headaches are believed to be stipulated by widening of blood vessels in the brain. Sumatriptan causes vasoconstriction of the carotid arterial bed which provides extracranial and intracranial tissues with blood without a significant impact on cerebral blood flow. It also inhibits activity of receptor which are responsible for transmission of pain signals by nerves to the brain.



Dosage and direction

Treatment with Sumatripan should be done just before the starting of a migraine attack. Recommended oral dose of adults is 25-50 mg, the dose maybe increased up to 100 mg if necessary. The medication is effective at any stage of the attack but if it does not help during the attack additional dose should not be taken. Treatment with Sumatriptan should be continued to prevent the next attack. Tablet of Sumatriptan should be swallowed whole, take it with a big glass of water. Usual intranasal dose of 5-20 mg may be increased to the maximum dose of 40 mg daily.



Precautions

Sumatriptan is used only to treat an acute, classic migraine attack or a cluster headache, it should not be used for treatment of certain unusual types of migraine. Patients with uncontrolled high blood pressure should not use Sumatriptan.



Contraindications

Hypersensitivity, basal, ophtalmoplegic, hemiplegic forms of migraine, ischemic heart disease (including suspected it), angina (including angina Printsmetala), myocardial infarction (also in history), hypertension, peripheral arterial occlusive disease, stroke or transient cerebrovascular accident (also in history), liver and kidney failure. Cautiousness should be exercised in patients with epilepsy (including any condition with low epileptic threshold), hypertension, pregnancy, breastfeeding, in infants and adolescents (younger than 18 y.o.), in patients older than 65 y.o.; simultaneous intake of medications which contain ergotamine and its derivatives, MAO inhibitors, and also during the period of 14 days after their cancellation.



Possible side effect

This medication is usually well tolerated and adverse reactions are not expected. Most frequent side effects include pain or tightness in the chest or throat, tingling, flushing, weakness, dizziness, abdominal discomfort, sweating, nasal irritation, and injection site reactions. Allergic reactions as adverse reactions of organism to Sumatriptan are also possible.



Drug interaction

Co-administration with ergotamine and medications containing ergotamin may develop a continued spasm of blood vessels (the interval between administration of these medications must be at least 24 h). Interaction of Sumatriptan and MAO inhibitors (isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine (Matulane)) is also possible resulting in increased concentration of Sumatriptan. Concomitant use of Sumatriptan with selective serotonin reuptake inhibitors or SSRIs, including fluoxetine (Prozac), citalopram (Celexa), paroxetine (Paxil), and sertraline (Zoloft) or serotonin and norepinephrine reuptake inhibitors, including venlafaxine (Effexor), duloxetine (Cymbalta), and desvenlafaxine (Pristiq) may promote weakness, hyperreflexia and poor coordination of movements.



Missed dose

Sumatriptan is not meant for regular use, it is taken only during an attack.



Overdose

Be especially attentive to such symptoms as bluish tinge to the skin, convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor as they may be signs of Sumatriptan overdose. Inform your health care advisor immediately about your condition nor seek for emergency medical help.



Storage

Store this medication at a temperature of 2-30 C (36-86 F) in a tight container resistant to light and moisture.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.



Common use Naproxen sodium belongs to a class of non-steroidal anti-inflammatory drugs (NSAIDs). This medication is used to reduce intense pain, inflammation and stiffness caused by conditions like osteoarthritis, rheumatoid arthritis, psoriatic arthritis, etc. It can be also applied in other cases. Dosage and direction Take Anaprox by mouth with a glass of water, with or without food. Avoid cutting, crushing or chewing this medicine. Do not take the medicine more often than it is prescribed. Do not give up taking it except on the advice of your doctor. It may need time for the medicine to help. Consult your doctor concerning proper dose for you. Precautions Before taking Anaprox tell your doctor or chemist if you are allergic to it; or if you have other allergies. Naproxen, like other NSAIDs, can inhibit the excretion of sodium and lithium. Be cautious when using this drug along with lithium supplements. Avoid drinking alcohol and smoking while being treated with this medication. Aged people can be more sensitive to side effects of the medicine. During pregnancy this treatment should be used only when strongly necessary. As this medicament can be absorbed by skin, women who are pregnant or may become pregnant should not manipulate this medicine. Contraindications Anaprox should not be used by patients with sodium-sensitive hypertension as well as by patients having demonstrated a reaction of hypersensitivity to it. Possible side effect The most common side effects are dry mouth, dizziness, irritability, sedation, insomnia, urinary retention, etc. A very serious allergic reaction rarely occurs. Many people using this medicine do not have serious side effects. Turn to your doctor or pharmacist for more details. In case you notice the effects not listed here, contact your doctor or pharmacist. Drug interaction Tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use before using this medication. Anaprox can interact with: * NSAIDs of the salicylate family (Aspirin) * anticoagulants. Turn to your doctor or pharmacist for more details. Missed dose If you have missed your dose, take it as soon as you remember. If you see that it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not take your dose twice. Overdose If you think you have used too much of this medicine seek emergency medical attention right away. The symptoms of overdose usually include chest pain, nausea, irregular heartbeat, and feeling light-headed or fainting. Storage Store your medicines at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store your drugs in the bathroom. Keep all drugs away from reach of children and pets. Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.Common use

Imdur belongs to nitrates. Effects of its active substance, Isosorbide mononitrate, consist in dilatation of (widening) of blood vessels and making it easier for the heart to pump. Imdur is used in treatment of angina attacks (chest pain). Other similar nitrates drugs include isosorbide dinitrate (Dilatrate-SR, Isochron, Isordil Titradose) and nitroglycerin (NitroQuick, Nitrolingual, Nitrostat, Nitro-Dur ).



Dosage and direction

The recommended dose of Imdur is 20 mg of immediate release tablets taken two times a day. Take the next dose at least seven hours later the previous dose to avoid tolerance. If you use The dose extended release tablets, the dose is 30-240 mg taken one time a day.



Precautions

You should not take Imdur if you use sildenafil (Viagra) due to possible serious side effects. If you are allergic to isosorbide dinitrate, (Isochron, Isordil, Dilatrate), isosorbide mononitrate, or nitroglycerin you should not take Imdur. Also do not use the drug if you have early signs of a heart attack such as chest pain or heavy feeling, nausea, sweating, pain spreading to the arm or shoulder, general ill feeling.

Before taking Imdur, notify your health care advisor if you have congestive heart failure, low blood pressure, or kidney disease. At the beginning of treatment Imdur may cause serious headaches. Do not use Imdur to treat angina attack that has already started. This medication is used to prevent angina attack so use it according to instructions of your doctor. Do not stop taking this medication suddenly as it may cause a severe angina attack. Inform your doctor if you have congestive heart failure, low blood pressure, or kidney disease. Rise slowly from a sitting or lying position unless you may have a severe drop in blood pressure.



Contraindications

Imdur is contraindicated in the patients with hypersensitivity or rare and unpredictable reactions to other nitrates or nitrites.



Side effects

The most frequent side effect of Imdur is headache, causing dizziness, palpitations, a severe drop in blood pressure when rising from a sitting position, weakness.



Drug interaction

Concomitant use with Sildenafil (Viagra), vardenafil (Levitra), or tadalafil (Cialis) may dangerously decrease the blood pressure and is contradicted. Do not combine Imdur with calcium channel blockers such as diltiazem (Dilacor, Tiazac, Cardizem) and verapamil (Isoptin, Isoptin SR, Calan, Verelan, Verelan PM, Covera-HS)



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double doses of Imdur. Take your usually dose next day in the same regularly time.



Overdose

Symptoms of overdose include fast or pounding heartbeats, nausea, vomiting, fever, confusion, dizziness a severe throbbing headache, spinning sensation, vision problems, stomach pain, bloody diarrhea, sweating, trouble breathing, cold or clammy skin, fainting, feeling light-headed, seizure.



Storage

Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Common use

Naprolen is in the group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to treat pain and inflammation in such conditions as arthritis, tendinitis, bursitis, ankylosing spondylitis, gout or menstrual cramps. It works by reducing hormones that cause inflammation and pain in the body.



Dosage and directions

Take the medicine exactly as prescribed by your doctor. Do not use Naprelanin larger amounts or longer than prescribed. Do not crush, chew or break tablet. Swallow the pill whole. your doctor may want to check you on a regular basis to make sure this medication is not causing harmful effects. Do not miss any scheduled visits to your doctor.



Precautions

Discuss with your doctor all conditions you may have especially the following:

a history of heart attack, stroke, or blood clot;heart disease, congestive heart failure, high blood pressure; a history of stomach ulcers or bleeding; liver or kidney disease; asthma; polyps in your nose;a bleeding or blood clotting disorder; or if you smoke.

Contraindications

Tell your doctor about all prescribed and not prescribed medications. Discuss with your doctor if you take cold, allergy, or pain medications before using Naprelan. Do not drink alcohol while taking naproxen. Alcohol can increase the risk of stomach bleeding caused by naproxen. Avoid prolonged exposure to sunlight. Naproxen can make your skin more sensitive to sunlight, and a sunburn may result. Wear protective clothing and use sunscreen when you are outdoors.



Possible side effects

Seek for medical attention immediately if any of the following effects occurs: severe allergic reactions (hives, difficulty breathing; swelling of your face, lips, tongue, or throat), chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance; black, bloody, or tarry stools; coughing up blood or vomit that looks like coffee grounds; swelling or rapid weight gain; urinating less than usual or not at all; nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; bruising, severe tingling, numbness, pain, muscle weakness; or fever, headache, neck stiffness, chills, increased sensitivity to light, purple spots on the skin, and/or seizure (convulsions).

Less serious side effects are: dizziness, headache, nervousness; upset stomach, mild heartburn or stomach pain, diarrhea, constipation; bloating, gas; blurred vision; skin itching or rash; or ringing in your ears.



Drug interaction

Before using Naprelan tell your doctor if you use the following antidepressants :citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor) as a contemporary use of them with Naprelan can lead to bruise or easy bleeding. Also tell you doctor about the following medicines you may take: a blood thinner such as warfarin (Coumadin); lithium (Eskalith, Lithobid); methotrexate (Rheumatrex, Trexall); diuretics (water pills) such as furosemide (Lasix); steroids (prednisone and others); aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), naproxen (Aleve, Naprosyn), meloxicam (Mobic), piroxicam (Feldene), and others; or an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), and others.



Missed dose

Since naproxen is sometimes taken only when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.



Overdose

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include nausea, vomiting, stomach pain, confusion, drowsiness, black or bloody stools, coughing up blood, shallow breathing, fainting, or coma.



Storage

Store Naprelan at room temperature, between 68 and 77 degrees F (20 and 25 degrees C) away from heat, moisture, and light. Do not store in the bathroom. Keep it out of the reach of children and away from pets.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Common use Tizanidine belongs to a class of muscle relaxants. It is applied in treatment of spasms, cramping, and tightness of muscles. Tizanidine is also prescribed off-label for migraine headaches and as an anticonvulsant. Dosage and direction Take Tizanidine by mouth with a glass of water, with or without food. Avoid cutting, crushing or chewing this medicine. Do not take the medicine more often than it is prescribed. Do not give up taking it except on the advice of your doctor. It may need time for the medicine to help. Consult your doctor concerning proper dose for you. Precautions Avoid drinking alcohol and smoking while being treated with this medication. Aged people can be more sensitive to side effects of the medicine. Inform your doctor if you have kidney or liver disease, high blood pressure; if you are pregnant or breast-feed. Contraindications Tizanidine should not be used by pregnant/nursing women or children as well as by patients having demonstrated a reaction of hypersensitivity to it. It is contraindicated to use tizanidine together with moderate or potent CYP1A2 inhibitors. Possible side effect The most common side effects are drowsiness, constipation, headache, dizziness and vomiting, diarrhea, yellowing of the skin or eyes. A very serious allergic reaction rarely occurs. Many people using this medicine do not have serious side effects. Turn to your doctor or pharmacist for more details. In case you notice the effects not listed here, contact your doctor or pharmacist. Drug interaction Before taking Tizanidine tell your doctor or chemist of all prescription and non-prescription medicines you are taking. Tizanidine should not be used with * antidepressants, esp. fluvoxamine * grapefruit juice * medicines for high blood pressure * medicines for pain (like codeine, morphine, and hydrocodone) * medicines for sleep * some antibiotics (like levofloxacin, ofloxacin). Turn to your doctor or pharmacist for more details. Missed dose If you have missed your dose, take it as soon as you remember. If you see that it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not take your dose twice. Overdose If you think you have used too much of this medicine seek emergency medical attention right away. The symptoms of overdose usually include chest pain, nausea, irregular heartbeat, and feeling light-headed or fainting. Storage Store your medicines at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store your drugs in the bathroom. Keep all drugs away from reach of children and pets. Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Common use

Pyridium is an analgesic of urinary tract. It is not know hao it works. It is used to relieve pain, burning, urgenvy, frequent urination and discomfort caused by irritation of the lower urinary tract.



Dosage and directions

Take Pyridium as prescribed by your doctor. Take it orally with food.



Precautions

Tell you doctor about all medical conditions you may have especially if you are pregnant, planning to become pregnant or breastfeeding, if you have any allergy to medicines or food, a history of certain blood problems (hemolysis), an enzyme deficiency called glucose-6-phosphate dehydrogenase (G-6-PD) deficiency or a family history of this deficiency.



Contraindications

You should not use Pyridium if you have an allergy to any of its components or you have decreased kidney function.



Possible side effects

No common side effect of Pyridium were reported. Severe side effects include severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blue or purple skin color; decreased urination; loss of appetite; unusual fatigue; vomiting; weight loss; yellowing of the skin or eyes.Seek urgent medical help if one of the listed above severe side effects occurs.



Drug interaction

No specific interactions with Pyridium were reported.



Missed dose

If you miss a dose of Pyridium, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.



Overdose

Symptoms of Pyridium overdose are bluish color of skin, yellowing of the skin or eyes, vomiting. If you suspect an overdose, seek urgent medical attention.



Strorage

Store Pyridium at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Pyridium out of the reach of children and away from pets.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Additional information
Dose

100mg, 25mg, 50mg

Pack

10pills, 120pills, 20pills, 30pills, 60pills, 90pills

Dose

500mg

Pack

120pills, 180pills, 30pills, 360pills, 60pills, 90pills

Dose

20mg, 30mg, 40mg, 60mg

Pack

120pills, 180pills, 240pills, 30pills, 360pills, 60pills, 90pills

Dose

250mg, 500mg

Pack

120pills, 180pills, 30pills, 360pills, 60pills, 90pills

Dose

2mg, 4mg

Pack

120pills, 150pills, 180pills, 30pills, 60pills, 90pills

Dose

200mg

Pack

120pills, 180pills, 30pills, 360pills, 60pills, 90pills